ABOUT US The Medicinal Organic Chemistry Group is a research group at the Research Institute for Medicines (iMed) focused on the development of new scaffolds to target diseases such as cancer, malaria and tuberculosis. MedOrgChemGroup
We are pleased to announce that a new research article involving members of the MOC group has been accepted for publication in ACS Medicinal Chemistry Letters. The article, entitled “Discovery of a Novel Chemical Scaffold for Dual MDM2 and MDM4 Inhibition”, reports the discovery of a novel chemical scaffold targeting both MDM2 and MDM4, two important proteins involved in the regulation of the tumour suppressor protein p53. The development of compounds capable of simultaneousl
The project, entitled “From CHemical design to MEchanisms: an innovative pipeline for optimization and characterization of anti-LEISHmania new scaffolds”, has been awarded funding under the Scientific Research and Technological Development Projects (SR&TD) programme, in the area of Clinical Medicine, Immunology and Infection. Project reference: 2025.18452.PTDC We are particularly pleased to be part of this exciting project, led by Principal Investigator Dr. Sofia Cortes, from
We are delighted to welcome the newest members of our research group - Iara Silva, Sofia Régio, David Pires, Teresa Moura and Ana Castro! This year, we are joined by a group of students who bring fresh perspectives, curiosity, and enthusiasm to our work. Each of them will contribute to ongoing projects while developing their own scientific path within the group. We are excited to support their growth, celebrate their achievements, and work together toward new discoveries. To
