Habilitation Defense by Maria Santos Highlights Project Progress in Developing PROTACs for Mutant p53 Degradation

On Tuesday, 10 February, the coordinator of our project, M. M. M. Santos, successfully defended her Habilitation in Pharmacy, with specialization in Pharmaceutical Chemistry and Therapeutics, at the Faculty of Pharmacy, University of Lisbon. Her habilitation work, titled “Medicinal Chemistry Strategies for Developing p53‑Targeted Anti‑Cancer Therapeutics,” underscores her long‑standing commitment to advancing innovative therapeutic strategies against cancer. During the habilitation presentation, was showcased the ongoing work from the current project, including recent progress on the design and optimization of PROTAC molecules aimed at degrading mutant p53.

By integrating this cutting‑edge work into her habilitation, Santos highlighted the project’s scientific relevance, and its potential impact on future cancer therapeutics. We congratulate her on this important accomplishment and look forward to the continued advancement of our shared mission to develop next‑generation p53‑targeted therapies.

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